Alzheimer's disease & dementia

Scientists develop drug that slows Alzheimer's in mice

A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, published May 14 ...

Parkinson's & Movement disorders

Unleashing the watchdog protein

McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The ...

Neuroscience

Scientists show how nerve wiring self-destructs

Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that ...

Neuroscience

Researchers identify how cells control calcium influx

(Medical Xpress)—When brain cells are overwhelmed by an influx of too many calcium molecules, they shut down the channels through which these molecules enter the cells. Until now, the "stop" signal mechanism that cells ...

Medical research

Scientists find clues to some inherited heart diseases

(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms of muscular dystrophy ...

Medical research

Brain research shows two parents may be better than one

A team of researchers at the University of Calgary's Hotchkiss Brain Institute (HBI) have discovered that adult brain cell production might be determined, in part, by the early parental environment. The study suggests that ...

Immunology

Immune response linked to key enzyme

(Medical Xpress)—A previously unknown function of a family of enzymes familiar to biologists may contribute to scientists' understanding of signaling molecules involved in the body's immune response and could help in the ...

Oncology & Cancer

Genetic master controls expose cancers' Achilles' heel

In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, Whitehead Institute scientists have discovered a set of powerful gene regulators dubbed "super-enhancers" that control cell state ...

Oncology & Cancer

Study reveals how melanoma evades chemotherapy

Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise, and raises the possibility ...

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