Genetic mutations caused by rearranged chromosomes drive the development and growth of certain colorectal cancers, according to new research conducted by Weill Cornell Medicine investigators.
Jul 12, 2017
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Scientists at St. Jude Children's Research Hospital comprehensively characterized oncogenic fusions in pediatric cancer, providing proof-of-principle for genetic engineering-based therapies.
Apr 5, 2023
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Cancer researchers must use one of the world's fastest computers to detect which versions of genes are only found in cancer cells. Every form of cancer, even every tumour, has its own distinct variants.
Feb 2, 2015
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Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit ...
Jun 7, 2013
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After years of development, engineering and enhancement, researchers at St. Jude Children's Research Hospital have made publicly available a software system that enables better detection of gene fusions. The system, called ...
Jun 15, 2020
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A fusion gene is a new gene made by joining parts of two different genes. The current thought is that fusion genes can happen in cells with unstable genome when part of the DNA from one chromosome moves to another chromosome. ...
Jan 28, 2019
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Researchers at Nagoya University in Japan have discovered a receptor, sigma-1 receptor, and a protein, ATAD3A, that are associated with Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. Since there ...
Apr 26, 2023
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It sounds like a plot from a Quentin Tarantino movie—something sets off natural killers and sends them on a killing spree.
Jun 16, 2021
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Cardiomyocytes fuse during cardiac development and regeneration. A scientist of the German Centre for Cardiovascular Research (DZHK) discovered these previously unknown processes with the aid of genetically modified zebrafish ...
Feb 9, 2018
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An international team of researchers, including Lukas Kenner from the Clinical Department of Pathology at MedUni Vienna, has discovered a specific combination of mutations and new gene fusions, which are heavily implicated ...
May 11, 2015
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