After years of development, engineering and enhancement, researchers at St. Jude Children's Research Hospital have made publicly available a software system that enables better detection of gene fusions. The system, called ...
Jun 15, 2020
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Acute myeloid leukemia (AML) mainly affects children, with often poor prognosis despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children ...
Oct 30, 2019
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A research study published in the journal Neoplasia and led by principal investigator Nallasivam Palanisamy, Ph.D., associate scientist in the Vattikuti Urology Institute at Henry Ford Health System, has identified a novel ...
Oct 2, 2019
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University at Buffalo researchers have identified the first human-specific fusion gene—a hybrid of two genes—implicated in Alzheimer's disease. The finding suggests that a neurotransmitter receptor, previously successful ...
May 16, 2019
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Developed by researchers at the Garvan Institute of Medical Research, this potential diagnostic method screens a cancer sample for 'fusion genes', estimated to be linked to one in five cancers, and may provide a more accurate ...
Mar 27, 2019
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White blood cells, also known as monocytes, play a key role in the immune system's response to infection. They have been shown to fuse and form multinucleated giant cells (MGCs) during inflammatory reactions, or in response ...
Jan 15, 2019
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The key genetic events responsible for initiating the early stages of a type of childhood leukaemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the 'founder' genetic mutation ...
Apr 5, 2018
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Researchers at Charité's NeuroCure Cluster of Excellence have successfully identified the mechanism behind rapid signal transmission. Their work, published in the current issue of Nature Neuroscience, shows that bridging ...
Dec 14, 2017
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(HealthDay)—The fibroblast growth factor receptor 3 (FGFR3) transforming acidic coiled-coil containing protein 3 (TACC3) (FT3) gene fusion recruits endogenous TACC3 away from the mitotic spindle, resulting in errors in ...
Sep 18, 2017
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A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.
Aug 30, 2017
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