In preclinical experiments, University of Alabama at Birmingham researchers have revealed a key missing piece of the Alzheimer's disease puzzle. That allowed proof-of-concept experiments—using an existing drug—that dramatically ...
Jan 15, 2020
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New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This, according ...
Feb 11, 2019
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In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy. But even as these agents prove themselves against several forms of leukemia and lymphoma—and, ...
Oct 30, 2018
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A team of Massachusetts General Hospital (MGH) Cancer Center researchers has determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation. In their ...
Aug 28, 2018
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In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine—a commonly used veterinary anesthetic—can lift a person out of a deep depression within minutes of its ...
Jun 21, 2018
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A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a potential approach against Alzheimer's disease. In studies with mice, the researchers were able to show that blocking a particular ...
May 4, 2018
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Making tiny changes to existing diabetes treatments can alter how they interact with cells, and potentially make the medicines more effective.
Apr 23, 2018
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A newly discovered cellular messaging mechanism could lead to a new way to deliver therapeutics to tissues affected by disease, according to a new study from Harvard T.H. Chan School of Public Health. Researchers found that ...
Sep 27, 2017
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Cornell University researchers have produced for the first time an image of P2X7, a receptor associated with chronic pain. Visualizing the shape of the receptor has also allowed them to make a second groundbreaking discovery: ...
Apr 14, 2017
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A study led by researchers at the Hospital del Mar Medical Research Institute (IMIM) and the Faculty of Medicine in Charité Hospital, Berlin demonstrates that the cholesterol present in cell membranes can interfere with ...
Feb 23, 2017
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