Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane.
In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine—a commonly used veterinary anesthetic—can lift a person out of a deep depression within minutes of its ...
Jun 21, 2018
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619
Regular exposure to cannabis may have a harmful impact on sociability. For some consumers, studies show that it may lead to withdrawal and reduced social interactions. However, the brain network and the mechanisms involved ...
Jul 8, 2020
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187
As the HIV virus glides up outside a human cell to dock and possibly inject its deadly cargo of genetic code, there's a spectacularly brief moment in which a tiny piece of its surface snaps open to begin the process of infection.
Feb 2, 2024
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111
Cornell University researchers have produced for the first time an image of P2X7, a receptor associated with chronic pain. Visualizing the shape of the receptor has also allowed them to make a second groundbreaking discovery: ...
Apr 14, 2017
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144
In preclinical experiments, University of Alabama at Birmingham researchers have revealed a key missing piece of the Alzheimer's disease puzzle. That allowed proof-of-concept experiments—using an existing drug—that dramatically ...
Jan 15, 2020
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Eric Prossnitz, Ph.D., and his team hope to help 93 million obese Americans fight their fat.
Feb 6, 2020
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407
Contrary to expectations that the neurotransmitter GABA only inhibited neuronal firing in the adult brain, RIKEN-led research has shown that it can also excite interneurons in the hippocampus of the rat brain by changing ...
Nov 25, 2011
1
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A study by scientists of the German Center for Neurodegenerative Diseases (DZNE) points to a potential approach against Alzheimer's disease. In studies with mice, the researchers were able to show that blocking a particular ...
May 4, 2018
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6
HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.
May 25, 2012
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