A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.
Nov 8, 2019
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Researchers led by the University of Birmingham have found a potential new target to treat inflammatory disease.
Nov 7, 2019
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For years, scientists have used cells grown in petri dishes to study the metabolic processes that fuel the immune system. But a new report in Immunity suggests looking outside the dish and into living organisms gives a drastically ...
Oct 11, 2019
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On the morning of Oct. 7, I woke up with the message from a colleague saying that "HIF got the 2019 Nobel Prize in Physiology or Medicine whoo hooo." That's exciting news for young researchers like me who are beginning our ...
Oct 9, 2019
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When it comes to repairing injured tissue, specialized cells in the body known as fibroblasts are called into action. Fibroblasts give rise to healing cells called myofibroblasts, which generally is good in the short term—but ...
Oct 4, 2019
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Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver's ability to properly metabolize fat. This effect is specific to fructose. Indeed, equally high levels of glucose ...
Oct 1, 2019
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Investigators at the Stanford University School of Medicine have pinpointed a molecular defect that seems almost universal among patients with Parkinson's disease and those at a high risk of acquiring it.
Sep 26, 2019
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A metabolic imbalance in some cancer patients following treatment with a checkpoint inhibitor drug, nivolumab, is associated with resistance to the immunotherapy agent and shorter survival, report scientists from Dana-Farber ...
Sep 25, 2019
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Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new drug delivery pathway that may help stop tumor growth and keep cancer from coming back in mice. In the preclinical study, the team found that ...
Sep 25, 2019
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The cardiovascular system is a complex network of veins, arteries and capillaries. Within that network, lymphatic vessels are critical to the heart's ability to heal in the event of a heart attack. When they're functional, ...
Sep 19, 2019
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