Medical research

To assess a cell's health, follow the glucose

A new spectroscopic technique reveals that glucose use in live cells provides valuable information about the functional status of cells, tissues, and organs. Shifts in a cell's use of glucose can signal changes in health ...

Diabetes

New insight into the biology of insulin release

In a new study, Yale researchers challenge a long-held assumption about how insulin-producing cells in the pancreas sense and respond to glucose. Their findings could lead to changes in the way that scientists approach the ...

Diseases, Conditions, Syndromes

New look at atherosclerosis

Atherosclerosis is the slow and progressive narrowing of arteries due to plaque formation. The atherosclerotic plaque forms by local proliferation of leukocytes and vascular smooth muscle cells (VSMCs) in the vessel wall ...

Diabetes

Tiny change has big effects, reverses prediabetes in mice

A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...

Immunology

Study explores role of metabolism in immune cell behavior

What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say ...

Medical research

Exercise may have different effects in the morning and evening

Researchers from the University of Copenhagen have learned that the effect of exercise may differ depending on the time of day it is performed. In mice, they demonstrate that exercise in the morning results in an increased ...

Diabetes

Stem-cell based therapy for type 2 diabetes and obesity

An article published in Experimental Biology and Medicine details a new therapeutic strategy for obesity and type 2 diabetes. The study, led by Dr. Bing Wang, Professor in the Department of General Surgery at Shanghai Ninth ...

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