Immunology

Molecular 'switch' reverses chronic inflammation and aging

Chronic inflammation, which results when old age, stress or environmental toxins keep the body's immune system in overdrive, can contribute to a variety of devastating diseases, from Alzheimer's and Parkinson's to diabetes ...

Medical research

Manipulating mitochondrial networks could promote healthy aging

Manipulating mitochondrial networks inside cells—either by dietary restriction or by genetic manipulation that mimics it—may increase lifespan and promote health, according to new research from Harvard T.H. Chan School ...

Medical research

Lessons from the worm: How the elderly can live an active life

When the tiny roundworm C. elegans reaches middle age—at about 2 weeks old—it can't quite move like it did in the bloom of youth. But rather than imposing an exercise regimen to rebuild the worm's body-wall muscles, researchers ...

Diabetes

Tiny change has big effects, reverses prediabetes in mice

A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...

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