Medical research

DNA changes in healthy bladder provide clues on how cancer arises

The first comprehensive study of DNA changes in healthy and diseased human bladder tissue has revealed that 'cancer-driving' mutations are common in healthy bladder tissue. The study, conducted by scientists at the Wellcome ...

Medications

New class of drug gives hope to some ovarian cancer patients

A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build ...

Oncology & Cancer

Research discovers how some cancers resist treatment

An international team of researchers led by Lucio Miele, MD, PhD, Professor and Chair of Genetics at LSU Health New Orleans School of Medicine, and Justin Stebbing, BM BCh MA, PhD, Professor of Cancer Medicine and Medical ...

Medical research

Researchers spot mutations that crop up in normal cells as we age

Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells and their progeny—called "somatic clones"—have no effect on our health, but a tiny fraction can ...

Oncology & Cancer

Analysis of 2,658 tumors sheds new light on mutations in cancer

A large-scale study conducted by KU Leuven and The Francis Crick Institute shows that 21% of tumors have double mutations, in which the exact same letter is mutated in both the maternal and paternal copy of your DNA. This ...

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