A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National ...
Dec 16, 2021
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Researchers at the John T. Macdonald Department of Human Genetics and John P. Hussman Institute for Human Genomics at the University of Miami Miller School of Medicine have found that inherited mutations in the MINAR2 gene ...
Jun 23, 2022
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St. Jude Children's Research Hospital scientists have mapped the effects of aberrant biological machinery that drives a deadly brain cancer called diffuse intrinsic pontine glioma (DIPG). The research included development ...
Dec 28, 2018
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Glioblastoma is one of the most devastating forms of cancer, with few existing treatment options. It is also a leading cause of cancer-related death in children and young adults. Scientists have 'reverse engineered' brain ...
Apr 16, 2019
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Scientists at the University of Bath have made further progress to understanding the role of one of the proteins that causes the neurodegenerative disorder Amyotrophic Lateral Sclerosis (ALS) and Parkinson's Disease (PD).
Mar 10, 2017
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Study published in Proceedings of the National Academy of Sciences suggests aging immune system plays a larger role in cancer incidence than previously thought. Findings may explain higher likelihood of men developing cancer ...
Feb 5, 2018
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Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread). A ...
Jan 5, 2019
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By the time we reach middle age, more than half of the oesophagus in healthy people has been taken over by cells carrying mutations in cancer genes, scientists have uncovered. By studying normal oesophagus tissue, scientists ...
Oct 18, 2018
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Imagine the thrill of discovery when more than 10 years of research on the origin of a common genetic disease, cystic fibrosis (CF), results in tracing it to a group of distinct but mysterious Europeans who lived about 5,000 ...
Sep 7, 2018
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A new study by KAIST researchers identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain mutation drivers for glioblastoma, ...
Aug 2, 2018
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