Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins. KRAS, for example, normally acts as an on/off switch for cellular proliferation, but mutations ...
May 11, 2023
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A University of Queensland study has found skin with few visible freckles or blemishes may still carry sun-damaged DNA mutations that can trigger cancer. Researchers from UQ's Frazer Institute Dermatology Research Center ...
May 11, 2023
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In a study of 17 people from five families, Johns Hopkins Medicine researchers say they found that ultra-lengthy DNA endcaps called telomeres fail to provide the longevity presumed for such people. Instead, people with long ...
May 4, 2023
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Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled—a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease. It is ...
Apr 13, 2023
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CU Boulder researchers have discovered a protein's crucial role in helping breast and ovarian tumors survive and thrive and have found that suppressing that protein kills cancer cells without harming healthy ones.
Apr 13, 2023
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An international coalition of biomedical researchers co-led by Alexander Bick, MD, Ph.D., at Vanderbilt University Medical Center has determined a new way to measure the growth rate of precancerous clones of blood stem cells ...
Apr 12, 2023
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Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans. The study, to be published March 17 in the Journal of Experimental Medicine, uses ...
Mar 17, 2023
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A new method to cure HIV—by transplanting HIV-resistant stem cells from umbilical cord blood—has yielded long-term successful results, say scientists. The approach was successfully used to treat the "New York patient," ...
Mar 16, 2023
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As the first clinical trial of the drug novobiocin is about to open for patients with cancers carrying BRCA gene mutations, new research at Dana-Farber Cancer Institute shows the drug poses a double threat to tumor cells.
Mar 14, 2023
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Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the ...
Mar 7, 2023
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