The old adage "use it or lose it" tells us: if you stop using your muscles, they'll shrink. Until recently, scientists thought this meant that nuclei—the cell control centers that build and maintain muscle fibers—are ...
Jan 25, 2019
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An interdisciplinary team of researchers has identified a new gene linked to human aortic aneurysms. By combining comprehensive genetic studies in the fruit fly, dataset searches and analysis of diseased human aortic tissue, ...
Apr 24, 2018
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Children who suffer from Hutchinson-Gilford Progeria syndrome age prematurely due to a defective protein in their cells. Scientists at Technische Universität München have now identified another important pathological factor: ...
Dec 17, 2014
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In pathology, cells and cell nuclei are usually examined using a microscope for bio-marker expressions in tumours. This analysis is used to weigh up the treatment options for patients who have cancer, for example. The certainty ...
Jul 14, 2014
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Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus ...
Feb 25, 2014
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Incorrectly positioned nuclei are not merely a sign but a possible cause of human congenital myopathies, a string of inherited muscle diseases, Victoria Schulman, graduate student at Weill Cornell Graduate School of Medical ...
Dec 16, 2013
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The human body has hundreds of different cell types, all with the same basic DNA, and all of which can ultimately be traced back to identical stem cells. Despite this fundamental similarity, a bone cell has little in common ...
Aug 29, 2013
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Neurobiologists at Heidelberg University have identified calcium in the cell nucleus to be a cellular "switch" responsible for the formation of long-term memory. Using the fruit fly Drosophila melanogaster as a model, the ...
Jul 9, 2013
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(Medical Xpress)—Researchers at Kanazawa University Graduate School of Medical Science in Japan have determined how APOBEC proteins mediate hypermutations that inhibit viral replication. They also identify the host factor ...
Jun 25, 2013
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Misshapen cell nuclei are frequently observed in the cells of people with cancer and other diseases, but what causes the abnormality—and why it is associated with certain disorders—has remained unclear.
Feb 19, 2013
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