Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus.
Apr 28, 2022
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In studies using mice grafted with human Ewing sarcoma tissue, researchers from Georgetown University Medical Center and colleagues have identified a biological pathway that is activated when tissue is starved of oxygen due ...
Apr 28, 2022
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The immune system remembers. Often this memory, primed by past encounters with threats like bacteria or viruses, is an asset. But when that memory is sparked by internal drivers, like chronic inflammation, it can prove detrimental, ...
Apr 27, 2022
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When the bacterium Helicobacter pylori infects the stomach, it causes gastric inflammation and increases the risk of stomach cancer. A team of researchers from Charité—Universitätsmedizin Berlin and the Max Delbrück ...
Apr 20, 2022
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Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells. By rewiring the inner workings ...
Apr 19, 2022
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Cancer cells can disrupt a metabolic pathway that breaks down fats and proteins to boost the levels of a byproduct called methylmalonic acid, thereby driving metastasis, according to research led by scientists at Weill Cornell ...
Apr 13, 2022
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While cancer therapies targeting specific genes or disease pathways can extend lives, they can also lead to highly resistant tumors when small reservoirs of cancer cells survive treatment, grow, and spread.
Mar 30, 2022
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Cancer cells initially confined to a single location in the body can eventually spread, or metastasize, to distant sites such as the bone, lung, liver and brain, where they take on new characteristics depending on the particular ...
Mar 23, 2022
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The immune system deteriorates with age, making COVID-19 particularly deadly in older people—but to date, no clinically available medication addresses this key risk factor. A study published today in Nature shows that an ...
Mar 21, 2022
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In laboratory experiments involving a class of mutations in people with a rare collection of immune system disorders, Johns Hopkins Medicine researchers say they have uncovered new details about how immune system cells respond ...
Mar 8, 2022
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