Immunologists at St. Jude Children's Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells.
Feb 25, 2021
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Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism ...
Feb 24, 2021
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Chronic inflammation drives the development of various cancers, including those of the skin, colon and pancreas. Investigators at Massachusetts General Hospital (MGH) who previously demonstrated high expression levels of ...
Feb 22, 2021
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The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search for effective cures. ...
Feb 16, 2021
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Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells. Because they ...
Feb 16, 2021
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A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received ...
Jan 27, 2021
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A fundamental process by which cellular components are degraded is autophagy. Defects in autophagy pathways are strongly associated with multiple human diseases, including neurodegenerative disorders and cancer. Despite their ...
Jan 20, 2021
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Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling the recycling of cell surface receptor proteins. The study, which will be published ...
Jan 14, 2021
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Using human-induced pluripotent stem cells engineered from a single family's blood samples, a gene signaling pathway linked to a higher risk for developing schizophrenia was discovered by scientists at The University of Texas ...
Dec 21, 2020
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DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate. The findings, published online ...
Dec 17, 2020
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