Medical research

Cancer cells can reuse apparent 'dead end metabolites'

Researchers at Winship Cancer Institute of Emory University have discovered that an apparent "dead end metabolite" has a previously unknown function regulating cell growth. The finding could guide efforts to target cancer ...

Genetics

New insights into the healing capacity of the heart

A group of researchers at Baylor College of Medicine, the Texas Heart Institute and the University of Texas Health Science Center at Houston reveals today in the journal Genes & Development new insights into the recently ...

Oncology & Cancer

Leukemia drug shows promise for treating a childhood brain cancer

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...

Oncology & Cancer

How lymphoma cells metastasize to the brain

Lymphomas in the central nervous system are rare but dangerous. Scientists at the German Cancer Research Center (DKFZ) have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous ...

Oncology & Cancer

Overcoming resistance in pancreatic cancer

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called "developing resistance," ...

Oncology & Cancer

Cracking the code of a brain cancer that keeps coming back

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with ...

Neuroscience

Signal blocks stem cell division in the geriatric brain

Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation. According to the researchers, the gene regulator Id4 controls whether ...

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