To inhibit the specific activity of a protein affected by a mutation using high doses of a drug is the usual treatment for many cancers. Except for the first instance in which this strategy is effective, it leads to treatment ...
Jul 1, 2020
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Like any cells in the body, cancer cells need sugar—namely glucose—to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose at a much higher rate than normal cells. However researchers from ...
Jun 17, 2020
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The sugar coating on cancer cells helps them thrive, and a new study indicates patients with cervical cancer who make antibodies to those sugars appear to do better when they also receive internal radiation therapy.
Jun 16, 2020
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Ionic channels—integral proteins in the cell membrane—are essential in several processes such as cardiac activity, nervous transmission, cell proliferation and the regulation of blood pressure. A study now published in ...
Apr 20, 2020
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Lung cancer is the predominant cause of cancer related deaths. Within the main types of lung cancers, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), NSCLC accounts for approximately 85%, with a poor ...
Mar 16, 2020
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A long-hidden metabolic system in cells could lead to new strategies for therapeutic cancer treatments in future.
Jan 21, 2020
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Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and ...
Jan 7, 2020
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Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein ...
Dec 27, 2019
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Palbociclib is clinically approved for use in treating breast cancer, but according to a new study, the molecular mechanism behind the drug's effectiveness is not what scientists had thought it was.
Dec 18, 2019
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Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor (EGFR), a protein that stimulates ...
Dec 12, 2019
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