Genetics

Researchers ID gene critical to human immune response

Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body's white blood cells to go on ...

Genetics

Possible role for Huntington's gene discovered

About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA repeats in the middle ...

Neuroscience

Study identifies new concepts for GLP-1 action in the brain

Researcher Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named the 2023 breakthrough of the year by the Science Magazine. Not only have millions of people ...

Oncology & Cancer

Breaking through the tumor's protective shield

The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune ...

Medical research

Scientists discover master regulator of skin development

The surface of your skin, called the epidermis, is a complex mixture of many different cell types—each with a very specific job. The production, or differentiation, of such a sophisticated tissue requires an immense amount ...

Oncology & Cancer

Uncovering a new pathway to halting metastasis

Metastasis, the process by which cancer cells leave the primary tumor and spread to other sites in the body, is responsible for more than 90 percent of cancer deaths. Thus, there is a significant need to improve the therapeutic ...

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