Medical research

Researchers provide novel insights into human skin aging

In human, the skin is one of the organs that exhibit early-onset aging-associated dysfunction. As a critical physical barrier, the skin is composed of a variety of cell types including fibroblasts and keratinocytes. Due to ...

Health

Why do older people heal more slowly?

I recently visited an 83-year-old patient in the hospital after EMTs rushed her to the ER with an infected leg wound. Her ordeal started inconspicuously when she bumped into the sharp edge of a table and developed a small ...

Medical research

Senescent cells may be good when it comes to a bad injury

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases. Now scientists have some of the first evidence that at a younger age at least, ...

Inflammatory disorders

Q&A: Controlling 'inflammaging,' inflammation that occurs with aging

A team at the CRCHUM—Université de Montréal's hospital research center—has discovered a new function for proteins responsible for DNA repair in the control of an inflammatory response in aging cells, also known as senescent ...

Oncology & Cancer

NSD2 enzyme appears to prevent cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging. Their experiments ...

Oncology & Cancer

Pregnancy reprograms breast cells, reducing cancer risk

An early age of pregnancy (25 years and younger) is known to reduce the overall risk of breast cancer by over 30%. CSHL Assistant Professor Camila dos Santos spent several years teasing out the molecular details behind the ...

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