Medical research

Nuclear export of opioid growth factor receptor is CRM1 dependent

In a study in the February 2016 Issue (241:3) of Experimental Biology and Medicine researchers at The Pennsylvania State University College of Medicine, led by Dr. Pat McLaughlin, discovered that a novel biological pathway, ...

Medical research

Researchers discover mutation involved in neurodegeneration

A mutation that increases the level of a special class of sphingolipids—molecules important to cell structure and signaling—can lead to neurodegeneration due to problems with neuronal membranes, reports a research team ...

Neuroscience

Slowness as organisation principle in the brain

The brain is so complex that its structure cannot be completely determined by genetics. Neuroscientists at the Ruhr-Universität Bochum (RUB) attempt to figure out which mechanisms nerve cells use to organise themselves. ...

Medical research

Hunting the ion channel

The electrical impulse that powers the workings of the brain and the heart begins with charged particles passing through cellular structures known as ion channels. Using the same technique used to decode the structure of ...

Medical research

Some pathogens use immune systems against us

Every moment of every day, our immune systems are battling to keep us healthy against an onslaught from invading organisms. But some of these invaders have evolved to use our very defences against us, writes Dr Stephen Graham, ...

Oncology & Cancer

Predicting cancers' cell of origin

A study led by researchers from Brigham and Women's Hospital suggests a new way to trace cancer back to its cell type of origin. By leveraging the epigenome maps produced by the Roadmap Epigenomics Program - a resource of ...

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