Genetics

Molecular cause underlying rare genetic disorder revealed

Virginia Tech scientists have revealed how a nonfunctioning version of an ordinary gene impairs brain structure and function. The findings help explain a genetic form of microcephaly—a condition where babies' heads are ...

Diseases, Conditions, Syndromes

Antibody neutralizes SARS and COVID-19 coronaviruses

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

Oncology & Cancer

Tailoring an anti-cancer drug for optimal tumor cell killing

In a study published this week in Science, Université de Montreal researchers report key structural and biochemical differences among a class of anti-cancer drugs known as PARP inhibitors. These distinguishing differences ...

Oncology & Cancer

How the immune system becomes blind to cancer cells

T cells play a huge role in our immune system's fight against modified cells in the body that can develop into cancer. Phagocytes and B cells identify changes in these cells and activate the T cells, which then start a full-blown ...

Neuroscience

Overactive brain waves trigger essential tremor

The source of essential tremor—a movement disorder that causes involuntary trembling of the hands, arms, and head—has been enigmatic, impeding the development of effective treatments for a condition that affects 4% of ...

Genetics

Researchers move beyond sequencing and create a 3-D genome

Like pirates on a treasure hunt, St. Jude Children's Research Hospital scientists have created the first 3-D map of a mouse genome and used it to discover scientific gold. The gold includes insight from machine learning into ...

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