Immunology

Live and let die: Protein prevents immune cell suicide

A protein called c-FLIP-R is critical to immune cell survival: If this molecule is missing, the cells kill themselves – and are thus no longer able to perform their job fighting off invaders. Now, scientists at the Helmholtz ...

Oncology & Cancer

Targeting pancreatic cancer drug resistance

Pancreatic cancer is one of the most deadly and intractable forms of cancer, with a 5-year survival rate of only 6%. Novel therapies are urgently needed, as conventional and targeted approaches have not been successful and ...

Medical research

Immune cells of the blood might replace dysfunctional brain cells

Blood-circulating immune cells can take over the essential immune surveillance of the brain, this is shown by scientists of the German Center for Neurodegenerative Diseases and the Hertie Institute for Clinical Brain Research ...

Oncology & Cancer

Scientists see potential in novel leukemia treatment

Scientists at Virginia Commonwealth University Massey Cancer Center may be one step closer to developing a new therapy for acute myeloid leukemia (AML) after discovering that the targeted agents obatoclax and sorafenib kill ...

Oncology & Cancer

New drug combination therapy developed to treat leukemia

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival ...

Psychology & Psychiatry

Preventing suicide: A critical next step

Doctors may in the future be able to take a blood test to determine if a patient is suicidal, hopefully decreasing the number of people taking their own lives.

Oncology & Cancer

MicroRNA makes triple-negative breast cancer homesick

Epithelial cells are homebodies – they like to attach to things and becoming detached initiates a form of cell suicide known as anoikis (literally "homeless" in Latin). But in order for cancer cells to metastasize they ...

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