Predicting cancer patient response to drugs that block DNA repair
Researchers have identified genetic tests that predict which cancer patients may benefit from the drugs in combination with chemotherapy.
Nov 6, 2023
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Researchers have identified genetic tests that predict which cancer patients may benefit from the drugs in combination with chemotherapy.
Nov 6, 2023
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Cancer cells are often a mess of mutations. About 20% to 25% of cancers involve mutations in a complex of molecules called SWI/SNF. Yet drugs designed to block SWI/SNF activity haven't always worked as expected. Researchers ...
Nov 3, 2023
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Researchers at MUSC Hollings Cancer Center believe that some drugs already approved by the FDA or currently in clinical trials could be repurposed for certain breast cancer patients whose cancer has become resistant to standard ...
Nov 2, 2023
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A new gene therapy for sickle cell disease has been deemed safe by a U.S. Food and Drug Administration advisory panel, paving the way for full approval by early December 2023.
Nov 2, 2023
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Researchers at the National Institutes of Health have developed a way to potentially increase the effectiveness of T cell–based immunotherapy treatments, such as CAR T-cell therapy, against solid tumors. T cells are specialized ...
Nov 1, 2023
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Researchers at the University of Wisconsin–Madison and Academia Sinica of Taiwan have harnessed a combination of lab-grown cells to regenerate damaged heart muscle.
Oct 31, 2023
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Patients with sickle cell disease may soon have two new treatments to try.
Oct 30, 2023
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Researchers at Nagoya University in Japan and their collaborators have used a biomarker based on microbubbles to evaluate the success of near-infrared photoimmunotherapy (NIR-PIT) treatment. Using ultrasound to track the ...
Oct 27, 2023
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Peripheral nerve injury (PNI) seriously affects people's quality of life. Stem cell therapy is considered a promising new option for the clinical treatment of PNI. Dental stem cells, particularly dental pulp stem cells (DPSCs), ...
Oct 26, 2023
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Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models. 5D4 works by binding to TopBP1 protein in cancer cells, disrupting ...
Oct 25, 2023
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