Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, a finding that could ...
Feb 24, 2023
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Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled.
Feb 15, 2023
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The immune system fights the coronavirus with antibodies and T cells. Scientists have a fairly good idea of how the virus avoids antibodies, including those promoted by vaccination, which is how variants of concern such as ...
Feb 14, 2023
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Researchers at The University of Texas MD Anderson Cancer Center have identified CD70 as being highly expressed on drug-resistant cancer cells in EGFR-mutant non-small cell lung cancer (NSCLC), highlighting a novel therapeutic ...
Feb 13, 2023
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Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. Patients with this subtype typically have poorer outcomes compared to other breast cancers, suggesting the need for improved treatments. ...
Feb 9, 2023
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A research team from LKS Faculty of Medicine, the University of Hong Kong (HKUMed) discovered that somatic deletion of a tumor suppressor gene AKTIP promotes luminal breast cancer development and resistance to endocrine therapy. ...
Feb 3, 2023
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Chimeric Antigen Receptor-expressing T cell (CAR-T) therapy involves re-engineering specific immune cells called T cells to target cancer. The treatment involves the production of CAR-T cells from the patient's own cells, ...
Feb 2, 2023
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A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. ...
Jan 26, 2023
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Inhibiting a particular protein in cancer-killing immune cells might improve the long-term effectiveness of CAR T-cell and other immune checkpoint therapies, according to a new study by researchers at The Ohio State University ...
Jan 24, 2023
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New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or an inflammatory response—are held in check by ...
Jan 24, 2023
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