Genetics

Mutant gene-targeted immunotherapy approach developed

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg-Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new ...

Medical research

Triangulation across data sources to understand COVID-19

One test of both the power and hunger of any individual or organization is the ability to master any and every new, sufficiently advanced technological opportunity that urgently presents itself to the world at large. For ...

Neuroscience

Mapping the brain's sensory gatekeeper

Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed ...

Neuroscience

Three types of cells help the brain tell day from night

Bright light at night interrupts the body's normal day-night cycles, called circadian rhythms, and can trigger insomnia. In fact, circadian rhythms play a major role in health. Disrupted day-night cycles have even been linked ...

Medical research

First lung map uncovers new insights into asthma

For the first time, researchers have mapped the building blocks of the human lungs and airways, in both asthma patients and normal people. The research from the Wellcome Sanger Institute, University Medical Center Groningen, ...

Oncology & Cancer

New cancer drug targets accelerate path to precision medicine

In one of the largest studies of its kind, researchers used CRISPR technology to disrupt every gene in over 300 cancer models from 30 cancer types and discover thousands of key genes essential for cancer's survival. The team, ...

Medical research

Engineered miniature kidneys come of age

In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, liver, intestine, ...

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