Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Oct 27, 2011
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Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The ...
Oct 21, 2011
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Antineoplastic agents such as immunotherapies and targeted therapies that specifically target signaling pathways in cancer cells are associated with thyroid dysfunction in 20%-50% of cancer patients taking them, which can ...
Oct 18, 2011
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Researchers at the Joslin Diabetes Center have identified for the first time two molecular pathways that are critical to activating a type of "good" fat found in the body, a discovery that could play an important role in ...
Sep 21, 2011
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Certain cancer signaling pathways that are activated in aggressive cancer can be detected very early, even in precancerous cells, among young African-American women at high risk for breast cancer. This may allow for earlier ...
Sep 20, 2011
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Curcumin, the main component in the spice turmeric, suppresses a cell signaling pathway that drives the growth of head and neck cancer, according to a pilot study using human saliva by researchers at UCLA's Jonsson Comprehensive ...
Sep 13, 2011
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New research led by Derya Unutmaz, MD associate professor, the Departments of Pathology, Medicine, and Microbiology at NYU School of Medicine and Mark Sundrud, PhD, of Tempero Pharmaceuticals, Inc., has identified a novel ...
Aug 10, 2011
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A team of researchers from the University of Utah and Brigham Young University has developed a mouse model of focal dermal hypoplasia, a rare human birth defect that causes serious skin abnormalities and other medical problems. ...
Jul 20, 2011
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Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the ...
Jul 17, 2011
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A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway ...
Jun 14, 2011
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