Chronic inflammation drives the development of various cancers, including those of the skin, colon and pancreas. Investigators at Massachusetts General Hospital (MGH) who previously demonstrated high expression levels of ...
Feb 22, 2021
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Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells. Because they ...
Feb 16, 2021
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A study led by Ludwig Chicago Co-director Ralph Weichselbaum and Yang-Xin Fu of the University of Texas Southwestern Medical Center has shown how bacteria in the gut can dull the efficacy of radiotherapy, a treatment received ...
Jan 27, 2021
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Yale scientists have identified a crucial biological link in the process that transforms certain complex sugars into hematopoietic stem and progenitor cells.
Dec 4, 2020
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Obesity is a serious global health problem and a risk factor for diseases such as type II diabetes, heart disease and fatty liver disease. A central element in the development of obesity is adipose tissue, which comprises ...
Nov 17, 2020
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Mount Sinai researchers have revealed new insights into how the body regulates craniofacial development in newborns, which can sometimes lead to birth defects such as cleft lip or palate.
Nov 12, 2020
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Deleting the TSC2 gene in specific lung cells of mice led to the activation of the mTORC1 signaling pathway and pulmonary disease characteristics consistent with human LAM disease, particularly in female breeder mice. These ...
Nov 9, 2020
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A study released today in STEM CELLS Translational Medicine points the way to a possible new avenue of treatment for ischemic stroke. The study, led by Annamaria Cimini, Ph.D., of the University of L'Aquila, and Liborio Stuppia, ...
Oct 7, 2020
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Tumors come in many shapes and forms—curable or deadly, solid or liquid, lodged inside the brain, bone, or other tissues. One thing they all have in common, however, is a knack for molecular deceit. It is often by posing ...
Sep 30, 2020
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A new study conducted by researchers at the University of Eastern Finland found that the PLCG2-P522R genetic variant, which protects against Alzheimer's disease, enhances several key functions of immune cells. The results ...
Sep 25, 2020
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