Oncology & Cancer
Molecular basis underlying colorectal cancer revealed
A team of scientists has unraveled the molecular mechanism behind one of the causes of colorectal cancer, and a treatment target.
Sep 15, 2020
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Page 12 - News tagged with cell-signaling pathways
Oncology & Cancer
Researchers identify metastasis driver in BRAF inhibitor resistant melanoma
Targeted therapy with BRAF-MEK inhibitors is an effective treatment for patients with advanced melanoma that cannot be surgically removed or has spread to other areas of the body. However, many patients become resistant to ...
Sep 2, 2020
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Oncology & Cancer
Researchers find potential to make brain cancers in children respond better to treatment
Brain cancer in children is always a devastating diagnosis, but McMaster University researchers may have found a way to have the most serious types of pediatric brain cancer respond better to therapies.
Aug 28, 2020
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Cardiology
A soft-hearted approach to healing
Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace. As adult cardiomyocytes ...
Aug 28, 2020
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Oncology & Cancer
International team identifies a new regulatory pathway in bladder cancer
Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled "GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma" in Science ...
Aug 20, 2020
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Medical research
New type of taste cell discovered in taste buds
Our mouths may be home to a newly discovered set of multi-tasking taste cells that—unlike most known taste cells, which detect individual tastes—are capable of detecting sour, sweet, bitter and umami stimuli. A research ...
Aug 13, 2020
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Oncology & Cancer
Scientists ID gene responsible for deadly glioblastoma
Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor. The discovery offers a promising new treatment target for a cancer that is always fatal.
Jul 14, 2020
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Medical research
Exploiting a signaling pathway disruption that sensitizes tumor cells to a particular drug
Scientists at LMU have shown that a signaling pathway that is disrupted in Ewing sarcoma specifically sensitizes tumor cells to a particular drug. The finding may open a route to new therapies for the most aggressive forms ...
May 18, 2020
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Neuroscience
Exploring the role of cells in the lateral thalamus in controlling fear behavior
Researchers at the Research Center for Natural Sciences and other institutes in Hungary have recently carried out a study investigating the involvement of brain regions other than the amygdala—more specifically, the lateral ...
Medical research
The YAP signal plays a crucial role in head-and-neck cancer onset
Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head and neck cancer over an extremely short period of ...
Mar 25, 2020
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