Oncology & Cancer

Rare developmental disorder linked to tumor-suppressing protein

CHARGE, which affects 1 in 10,000 babies, is an acronym whose letters stand for some of the more common symptoms of the condition: coloboma of the eye, heart defects, atresia of the choanae, retardation of growth and/or development, ...

Immunology

Sensitive balance in the immune system

Apoptosis is used by cells that are changed by disease or are simply not needed any longer to eliminate themselves before they become a hazard to the body—on a cellular level, death is part of life. Disruption of this process ...

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Immunology

Live and let die: Protein prevents immune cell suicide

A protein called c-FLIP-R is critical to immune cell survival: If this molecule is missing, the cells kill themselves – and are thus no longer able to perform their job fighting off invaders. Now, scientists at the Helmholtz ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

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