Oncology & Cancer

Breast cancer tumor suppressor gene silenced by low O2

Low oxygen can silence the BRCA1 tumor suppressor gene and contribute to the progression of cancer, according to a paper in the August 2011 issue of the journal Molecular and Cellular Biology. Silencing this particular gene ...

Oncology & Cancer

Genetics of melanoma chemoresistance

Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...

Oncology & Cancer

Indirectly influencing cancer's out-of-control cell replication

As differently as cancers or autoimmune diseases (such as multiple sclerosis, rheumatoid arthritis or psoriasis) affect people, they all have one characteristic in common: they are accompanied by increased cell proliferation. ...

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