A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may lead ...
Feb 8, 2012
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Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified a cellular protein that plays a central role in the formation of new blood vessels. The molecule is the protein Shc (pronounced ...
Nov 28, 2011
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Antineoplastic agents such as immunotherapies and targeted therapies that specifically target signaling pathways in cancer cells are associated with thyroid dysfunction in 20%-50% of cancer patients taking them, which can ...
Oct 18, 2011
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A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway ...
Jun 14, 2011
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A new research paper was published on the cover of Aging, titled "A chronic wound model to investigate skin cellular senescence."
May 1, 2023
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A new research paper titled "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity" has been published in Aging.
Jan 31, 2023
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There is growing evidence that the appearance and texture of the skin that is altered during the aging process are considerably enhanced by the accumulation of senescent dermal fibroblasts. These senescent cells magnify aging ...
Oct 31, 2022
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Alterations in a cellular signaling pathway called cAMP–CREB may help explain why the body clocks of people with bipolar disease are out of sync, according to a new European Journal of Neuroscience study.
Jun 16, 2014
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The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
Feb 8, 2013
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Pemphigus vulgaris is a life-threatening autoimmune skin disease that is occurs when the body's immune system generates antibodies that target proteins in the skin known as desomogleins. Desmogleins help to form the adhesive ...
Jan 9, 2013
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