A research team from Kumamoto University, Japan has developed an animal model that reproduces motor dysfunction and cerebellar neurodegeneration similar to that in spinocerebellar ataxia (SCA) by inhibiting chaperone-mediated ...
Sep 23, 2020
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For the first time, the UNC School of Medicine lab of Jonathan Schisler, MS, Ph.D., linked the specific biochemical changes to a protein called CHIP to specific disease characteristics of patients with a wide range of rare ...
Nov 6, 2019
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World-renowned cartographer of the brain, Scientia Professor George Paxinos, Conjoint Professor at UNSW, has discovered a hidden region of the human brain. The region is found near the brain-spinal cord junction and Professor ...
Nov 27, 2018
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The cerebellum is an area of brain at the back of your head involved in movement. Its neuronal circuitry is relatively simple compared to other areas, but scientists still have a lot left to learn regarding its role in motor ...
Jul 12, 2017
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While autoimmune cerebellar ataxia (a loss of muscle coordination) can lead to severe disability with some patients becoming wheelchair-bound, there are factors that may help to predict better immunotherapy response and neurological ...
Sep 28, 2015
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No cures are possible for most patients who suffer debilitating movement disorders called cerebellar ataxias.
Mar 23, 2015
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Neuronal death is a normal feature of brain development but also a defining feature of neurodegenerative diseases when improperly regulated. Results of a detailed and comprehensive analysis of transcriptome expression alterations ...
Feb 11, 2015
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A team of scientists has obtained intriguing insights into two groups of autism candidate genes in the mammalian brain that new evidence suggests are functionally and spatially related. The newly published analysis identifies ...
Jul 25, 2013
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Researchers from Massachusetts General Hospital (MGH) and Duke University have identified genetic mutations that appear to underlie a rare but devastating syndrome combining reproductive failure with cerebellar ataxia – ...
May 8, 2013
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A dysfunction of a certain Calcium channel, the so called P/Q-type channel, in neurons of the cerebellum is sufficient to cause different motor diseases as well as a special type of epilepsy. This is reported by the research ...
Mar 21, 2013
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