Immunology
Scientists identify unexpected player in intestinal immunity
With every meal, immune cells in the intestine stand like sentries at a citadel, turning away harmful bacteria but allowing vitamins and nutrients to pass.
Mar 14, 2012
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Page 3 - News tagged with chaperone proteins
Neuroscience
Researchers discover possible key to degenerative nerve diseases
(Medical Xpress) -- Researchers at the University of Wisconsin-Madison and collaborators have discovered a powerful new protein in the eye of the fruit fly that may shed light on blinding diseases and other sensory problems ...
Nov 17, 2011
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Immunology
Shedding more light on how the body controls our immune systems
The membrane attack complex (MAC) is a set of proteins typically formed on the surface of pathogen cell membranes. They punch tiny holes in an invading bacteria's membrane. The bacteria ultimately dies if enough holes are ...
Jan 5, 2022
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Alzheimer's disease & dementia
Study first to show pharmacological chaperone therapy prevents Alzheimer's in mice
Like pieces of tape that crumple, stick together, and can be turned into a ball, proteins that begin to lose their shape become sticky and tend to clump together. When this happens, rather than being transported to recycling ...
Jan 22, 2020
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Medical research
How molecular escorts help prevent cancer
The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide. New research conducted at Technical University of Munich (TUM) shows ...
May 21, 2019
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Medical research
Major step found in cellular response to stress caused by pathological insult
A new study conducted by researchers at The Wistar Institute revealed how a key protein residing in the endoplasmic reticulum (ER) helps cells respond to stress. This process is especially important for B cells to respond ...
Mar 6, 2018
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Cardiology
Protein helps protect tissues from damage after a heart attack
University of Cincinnati (UC) researchers have observed levels of HAX-1, an anti-cell death protein, drop significantly in mice after a heart attack and during heart failure resulting in cardiac cells dying at a higher than ...
Nov 16, 2015
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Medications
Viagra in combination with new drugs can have anti-cancer, antibacterial, therapeutic effects
Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How ...
Mar 9, 2015
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Medical research
Scientists find new cellular pathway defect in cystinosis
Scientists at The Scripps Research Institute (TSRI) have identified a new cellular pathway that is affected in cystinosis, a rare genetic disorder that can result in eye and kidney damage.
Feb 10, 2015
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Oncology & Cancer
Finding a target for tumor suppression
One of the hopes for victory against cancer hinges on naturally-occurring proteins whose job is to make their host cell die.
Feb 3, 2014
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