Diseases, Conditions, Syndromes

ICI need not be withheld in those with autoimmune disease

(HealthDay)—For patients with advanced melanoma, response to immune checkpoint inhibitors (ICIs) is similar for those with and without preexisting autoimmune disease (AID), according to a study published online Feb. 16 ...

Oncology & Cancer

Cancer specialist demonstrates safety of novel agent

A novel therapy designed to help stimulate the body's immune system response against cancer appears to be safe to use as alone or in combination with immune checkpoint inhibitors, according to an early phase clinical trial ...

Oncology & Cancer

A helping hand for cancer immunotherapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...

Oncology & Cancer

Reprograming T cells to attack solid tumors

An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...

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