Oncology & Cancer

Impact of epigenetics on the clinical management of cancer patients

In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...

Immunology

Neurogenesis—discovery of a new regulatory mechanism

Bassem Hassan's team at VIB/KU Leuven has discovered a previously unknown mechanism that is highly conserved between species and which regulates neurogenesis through precise temporal control of the activity of a family of ...

Medical research

More potent, inexpensive gene silencing agents described

Combining the therapeutic potential and advantages of existing oligonucleotide-based approaches to turn off disease-related genes, a type of single-stranded silencing RNAs (ss-siRNAs) has shown significantly improved potency ...

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