A new class of drugs that inhibits a 'master switch' involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.
Jun 22, 2021
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The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases. The ASH1L protein, however, has been challenging to target therapeutically.
May 14, 2021
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Many people live with chronic pain, and in some cases, cannabis can provide relief. But the drug also can significantly impact memory and other cognitive functions. Now, researchers reporting in ACS' Journal of Medicinal ...
May 12, 2021
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The virostatic agent remdesivir was developed to disrupt an important step in the propagation of RNA viruses, to which SARS-CoV-2 also belongs: the reproduction of the virus's own genetic material. This is present as RNA ...
May 10, 2021
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The highly infectious SARS-CoV-2 variant that recently emerged in South Africa, known as B.1.351, has scientists wondering how existing COVID-19 vaccines and therapies can be improved to ensure strong protection. Now, researchers ...
Apr 28, 2021
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SARS-CoV-2, the new coronavirus behind the current pandemic, infects humans by binding its surface-exposed spike proteins to ACE2 receptors exposed on the cell membranes.
Feb 3, 2021
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Nonalcoholic fatty liver disease (NAFLD) is a widespread condition in the Western World. Around 30% of the population have lipid droplets stored in their liver which diminish its function in the long term. Main causes for ...
Jan 25, 2021
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As one of the trendiest foods in the produce aisle, microgreens are known for adding a splash of color to a dish, a spicy kick to a salad—and a chunk of change to a grocery bill.
Jan 11, 2021
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Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will ...
Jan 7, 2021
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Emmanuelle Charpentier of France and Jennifer Doudna of the US on Wednesday won the Nobel Chemistry Prize for the gene-editing technique known as the CRISPR-Cas9 DNA snipping "scissors", the first time a Nobel science prize ...
Oct 7, 2020
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