In a prospective phase II study that involved patients with mismatch repair–deficient locally advanced rectal cancer, treatment with neoadjuvant single-agent, PD1 inhibitor dostarlimab resulted in a clinical complete response—as ...
Jun 9, 2022
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72
A new way in which cancer cells can repair DNA damage has been discovered by researchers at the University of Birmingham.
May 19, 2022
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151
It's one of the most heartbreaking things Adam Green, MD, sees as a pediatric oncologist: children who beat their cancer, only to see an incurable brain tumor arise five years later.
Sep 28, 2021
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64
Cancer cells sometimes develop resistance to the cytotoxic drugs used in chemotherapy. Figuring out why the treatment isn't working and why it may even defeat its own purpose is therefore important to understand.
Aug 5, 2021
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296
In the human gut, good bacteria make great neighbors.
May 26, 2021
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15
An innovative approach to treating bone tumors—starving cancer cells of the energy they need to grow—could one day provide an alternative to a commonly used chemotherapy drug without the risk of severe side effects, suggests ...
Jan 26, 2021
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69
UConn associate professor of pharmaceutics Xiuling Lu, along with professor of chemistry Rajeswari M. Kasi, was part of a team that recently published a paper in Nature Cell Biology finding a commonly used chemotherapy drug ...
Jun 18, 2020
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259
Due to their powerful tumour-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) ...
Dec 18, 2018
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25
McMaster University researchers have provided evidence of new cancerous cells they have termed cancer regenerating cells, which are responsible for the return of acute myeloid leukemia after remission.
Sep 10, 2018
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31
For a small percentage of cancer patients, treatment aimed at curing the disease leads to a form of leukemia with a poor prognosis. Conventional thinking goes that chemotherapy and radiation therapy induce a barrage of damaging ...
Dec 8, 2014
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