Oncology & Cancer
Confining cell-killing treatments to tumors
Cytokines, small proteins released by immune cells to communicate with each other, have for some time been investigated as a potential cancer treatment.
Jun 26, 2019
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Page 16 - News tagged with chimeric antigen receptor
Medical research
Henry Ford Cancer Institute treats its first patient with innovative 'living drug' therapy
Henry Ford Cancer Institute has treated its first patient with CAR T-cell therapy, an approach that uses engineered cells from a patient's immune system to destroy cancer. The altered cells remain active for years after the ...
Jun 18, 2019
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Oncology & Cancer
Primary findings from first-in-human immunotherapy trial show promise in treating neuroblastoma
Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In a promising development, researchers at Baylor College of Medicine released initial ...
May 2, 2019
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Medical research
UCSD patient gets first cancer treatment made from stem cells
A new form of cancer immunotherapy has been given to a University of California, San Diego Health patient in the first test of immune cells grown from stem cells.
Apr 16, 2019
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Oncology & Cancer
Mesothelin-targeted CAR T-cell therapy shows early promise in patients with solid tumors
A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according ...
Mar 31, 2019
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Oncology & Cancer
Researchers characterize mechanism of action of CAR T cells
The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells. ...
Feb 14, 2019
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Oncology & Cancer
Researchers identify experimental immunotherapy approach to target acute myeloid leukemia
University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential way to target a subtype of acute myeloid leukemia (AML) using chimeric antigen receptor (CAR) T-cell therapy, a form ...
Jan 4, 2019
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Oncology & Cancer
More than half of patients alive 2 years after receiving CAR-T therapy for diffuse large B-cell lymphoma in ZUMA-1 trial
A follow-up analysis of patients enrolled in a Phase I/II multi-center trial for diffuse large B-cell lymphoma (DLBCL) reported 51 percent of patients receiving an anti-CD19 chimeric antigen receptor (CAR T) called axi-cel ...
Dec 3, 2018
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Immunology
Study uncovers key parts of mechanism for activating T cells to fight cancer and other diseases
In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy. But even as these agents prove themselves against several forms of leukemia and lymphoma—and, ...
Oct 30, 2018
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Oncology & Cancer
How an idea from a lab may change cancer treatments
In recent years, researchers have begun to fight cancer by genetically engineering a patient's own immune system to target the disease. Quad Technologies, a company that grew out of a Northeastern research lab, has been developing ...
Oct 18, 2018
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