Through a structural and functional approach, researchers from the Icahn School of Medicine at Mount Sinai and Stanford University Medical Center identified physical binding sites for cholesterol in the brain's G-protein-gated ...
Aug 24, 2021
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The cholesterol drug alirocumab reduced low-density lipoprotein (LDL) cholesterol by 35.6% compared to placebo in adult patients with homozygous familial hypercholesterolemia (HoFH), according to a phase three clinical trial ...
Mar 30, 2020
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Hepatocellular carcinoma (HCC) is a deadly disease with no effective cure that develops in the context of liver diseases associated with chronic inflammation. A recent research article published in The Journal of Experimental ...
Mar 29, 2017
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Statin drugs are widely used to manage high cholesterol and reduce the risk of cardiovascular disease. But in a new review of more than 50 studies, researchers cite reductions in liver inflammation and improvements in other ...
Mar 24, 2017
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A recent analysis indicates that adding new therapies called anti-PCSK9 antibodies to other lipid-lowering treatments can help patients lower their LDL cholesterol levels.
Aug 1, 2016
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The nation's biggest pharmacy benefits manager has decided to cover two new drugs that lower artery-clogging cholesterol but raise concern over prices that can top $14,000 a year.
Oct 6, 2015
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Biotech drug giant Amgen has made two much-needed deals to replenish its stock of medicines in development as new competition to its lucrative biotech drugs threatens future revenue.
Sep 16, 2015
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The Food and Drug Administration has approved a Novo Nordisk diabetes drug as a treatment for obesity. It's the first injectable drug approved for weight loss.
Dec 23, 2014
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Between 1999 and 2012, the Food and Drug Administration gave its blessing to exactly zero new weight-loss drugs. Then, starting in June of last year, the agency approved two such medications, in a span of 20 days.
Jul 1, 2013
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British drugmaker AstraZeneca PLC plans to spend about $260 million on Omthera Pharmaceuticals Inc., a specialty drug developer with only 14 employees but has a potential treatment for patients who have high levels of fats ...
May 28, 2013
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