Neuroscience

Tangled path of Alzheimer's-linked brain cells mapped in mice

By studying laboratory mice, scientists at The Johns Hopkins University have succeeded in plotting the labyrinthine paths of some of the largest nerve cells in the mammalian brain: cholinergic neurons, the first cells to ...

Alzheimer's disease & dementia

Study hints at early sign of Alzheimer's degeneration

Researchers have moved one step closer to identifying targets for brain degeneration that occur decades before symptoms of Alzheimer's disease appear—a much sought-after clue that might open the door to early treatment.

Medical research

Two groups of neurons identified in causing Leigh syndrome

Leigh syndrome affects one in every 40,000 newborns and is produced by deficits in the mitochondria, which produce the energy needed for cells to function correctly. Thus, cells with a high energy demand, such as the brain ...

Neuroscience

Surfing on calcium waves: A larva's journey to becoming a fly

Eric Carl, in his much-loved children's book The Very Hungry Caterpillar, documents the transformation of a gluttonous caterpillar into a beautiful butterfly. For a scientist, metamorphosis poses many unaddressed questions. ...

Alzheimer's disease & dementia

Pathway of Alzheimer's degeneration discovered

Scientists at the Montreal Neurological Institute and Hospital (The Neuro) of McGill University have used a unique approach to track brain degeneration in Alzheimer's disease, uncovering a pathway through which degeneration ...

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