An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
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Researchers at RCSI, along with international collaborators within the ANGIOPREDICT research consortium, have discovered that chromosomal instability (where whole human chromosomes or parts of chromosomes are duplicated or ...
Oct 10, 2018
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Metastatic tumours are characterised by a high degree of chromosomal instability—that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether ...
Sep 26, 2018
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New insights into how Kaposi's sarcoma-associated herpesvirus (KSHV) induces genome instability and promotes cell proliferation could lead to the development of novel antiviral therapies for KSHV-associated cancers, according ...
Sep 13, 2018
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Greater knowledge of the mechanisms that contribute to the survival of tumour cells is key to vanquishing them. The study published today in the journal Cancer Cell, headed by Angel R. Nebreda, ICREA researcher at the Institute ...
May 24, 2018
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Researchers from Instituto de Medicina Molecular (iMM) João Lobo Antunes have found that a functional component of telomeres called TERRA has to be kept constantly in check to prevent telomeric and chromosomal instability, ...
Jan 23, 2018
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Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...
Jan 18, 2018
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Researchers from the Development and Growth Control Laboratory at IRB Barcelona have identified the cell types and molecular mechanism responsible for the unlimited growth potential of epithelial tumours (carcinomas) and ...
Sep 8, 2017
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To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) hope to answer with a new advance that could help doctors and their cancer patients ...
Aug 31, 2016
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Despite their especially compact and inaccessible structure, telomeres transcribe information like the rest of the DNA. The RNAs resulting from this process are called TERRA, and their function is essential in preserving ...
Aug 17, 2016
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