Cardiology

Flipping a molecular switch for heart fibrosis

A healthy heart is a pliable, ever-moving organ. But under stress—from injury, cardiovascular disease, or aging—the heart thickens and stiffens in a process known as fibrosis, which involves diffuse scar-like tissue. ...

Cardiology

Heart failure cases soar globally

The number of patients with heart failure worldwide nearly doubled from 33.5 million in 1990 to 64.3 million in 2017. That's the finding of a study published today in the European Journal of Preventive Cardiology, a journal ...

Medications

Histamine: an unexpected defender against heart and kidney damage

Chronic kidney disease and heart failure are critical medical problems worldwide, and are closely associated in a phenomenon known as "cardiorenal syndrome." The relationship between kidney dysfunction and heart dysfunction ...

Medical research

'Goldilocks' drug prevents chronic kidney disease in primates

Cells in any organ will die if their blood supply is cut off - such as during a heart attack, stroke, or organ transplant - but restoring circulation can also cause damage. Now a Massachusetts General Hospital (MGH) research ...

Medical research

Strategy proposed for preventing diseases of aging

Medicine focuses almost entirely on fighting chronic diseases in a piecemeal fashion as symptoms develop. Instead, more efforts should be directed to promoting interventions that have the potential to prevent multiple chronic ...

Medical research

Drug candidate leads to improved endurance

An international group of scientists has shown that a drug candidate designed by scientists from the Florida campus of The Scripps Research Institute (TSRI) significantly increases exercise endurance in animal models.

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