Diseases, Conditions, Syndromes

How to achieve a functional cure for chronic hepatitis B

More than half of people with chronic hepatitis B have a form of the disease in which the immune system almost never achieves sustained control, despite many years of treatment. According to current knowledge, those affected ...

Diseases, Conditions, Syndromes

Why severe fatty liver leads to liver damage

In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...

Oncology & Cancer

Novel AI blood test detects liver cancer

A novel artificial intelligence blood testing technology developed and used by Johns Hopkins Kimmel Cancer Center researchers to successfully detect lung cancer in a 2021 study has now detected more than 80% of liver cancers ...

Diseases, Conditions, Syndromes

Study provides basis for personalized hepatitis C aftercare

Even after chronic hepatitis C has been cured, portal hypertension remains the major factor driving the development of complications in advanced liver disease. In cooperation with researchers from Spain, a research team led ...

Immunology

Immune therapies against chronic hepatitis B

Hepatitis B virus (HBV) infection is global in nature and induces several liver diseases, such as chronic hepatitis B (CHB), cirrhosis of the liver (LC) and hepatocellular carcinoma (HCC). A total of 882,000 patients died ...

Diseases, Conditions, Syndromes

A roadmap for the future of hepatitis B therapy development

Worldwide, 880,000 people die each year as a result of infection with the hepatitis B virus (HBV). Antiviral drugs that can suppress replication of the virus are available. However, these must be taken for decades, as there ...

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