Immunology

Molecular clock influences immune cell responses

Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized ...

Medical research

Fat cells work different 'shifts' throughout the day

Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds.

Medical research

Micro-control of liver metabolism

Researchers at TIFR have discovered molecular anticipation of feeding in the liver that is essential to ensure that the body, after fasting, adapts to use incoming nutrients upon re-feeding. Their findings, published in the ...

Genetics

Risk of suicide—as well as depression—found in the genome

Yale researchers have discovered several genetic variants that signal the risk of serious suicide attempts and noted some variants have also been linked to major depressive disorder, they report Jan. 17 in the journal Translational ...

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Circadian rhythm

A circadian rhythm is a roughly-24-hour cycle in the biochemical, physiological or behavioral processes of living entities, including plants, animals, fungi and cyanobacteria (see bacterial circadian rhythms). The term "circadian", coined by Franz Halberg, comes from the Latin circa, "around," and diem or dies, "day", meaning literally "approximately one day." The formal study of biological temporal rhythms such as daily, tidal, weekly, seasonal, and annual rhythms, is called chronobiology.

Circadian rhythms are endogenously generated, and can be entrained by external cues, called Zeitgebers, the primary one of which is daylight. These rhythms allow organisms to anticipate and prepare for precise and regular environmental changes.

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