Oncology & Cancer

A helping hand for cancer immunotherapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have demonstrated the therapeutic potential of PRMT5 inhibitors to sensitize unresponsive melanoma to immune checkpoint therapy. PRMT5 inhibitors are currently ...

Medical research

Researchers discover potential boost to immunotherapy

Mount Sinai researchers have discovered a pathway that regulates special immune system cells in lung cancer tumors, suppressing them and allowing tumors to grow. The scientists also figured out how to interrupt this pathway ...

Oncology & Cancer

Starving leukemia cells by targeting amino acids

Cancer cells consume sugar at a higher rate than healthy cells, but they're also hungry for amino acids, the building blocks of proteins and other biomolecules. Researchers at Winship Cancer Institute of Emory University ...

Neuroscience

Researchers discover clues to brain changes in depression

In new pre-clinical research, scientists at the University of Maryland School of Medicine (UMSOM), led by Scott Thompson, Ph.D., Professor of Physiology, have identified changes in brain activity linked to the pleasure and ...

Oncology & Cancer

'Embattled' breast cancer drugs could be revived by new discovery

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells—known as the PI3 kinase (PI3K) pathway—but efforts to develop therapies targeting this pathway have ...

page 3 from 11