Several studies have reported a lack of gender diversity in clinical trials, with trials including mostly adult males; however, a recent review of publicly available registration data of clinical trials at the US Food and ...
Jan 11, 2018
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Nerve growth factor signals through receptors of the tropomyosin-related kinase (Trk) family, and research in animals has shown that inhibitors of Trks A, B, and C can reduce pain. Now a new study in the British Journal of ...
Nov 27, 2017
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A new analysis published in the British Journal of Clinical Pharmacology indicates that 'first-in-man' clinical trial protocols in the Netherlands often lack a consistent consideration of pharmacokinetic and pharmacodynamic ...
Oct 4, 2017
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A phase 1 clinical trial published in the British Journal of Clinical Pharmacology found that radavirsen—an antisense oligomer that inhibits the production of certain influenza proteins—is safe and well-tolerated in healthy ...
Sep 20, 2017
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Use of fluoxetine—the most commonly prescribed antidepressant—during pregnancy is linked with a slightly increased risk of malformations in infants, according to a recent analysis of published studies.
May 17, 2017
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Medicines that carry warnings about sleep disturbances do not seem to contribute to the amount of sleep disturbances in the general population, according to new 'real world' research. The findings, which are published in ...
Jun 8, 2016
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The new Concise Guide to PHARMACOLOGY 2015/2016 provides a valuable and unique overview of the key properties of more than 1,700 human drug targets, focusing on those exploited currently in the clinic or with future therapeutic ...
Jan 4, 2016
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Rational use of medicines is one of the most challenging problems in health systems worldwide. Kazan Federal University researchers conducted a practical study to assess the impact of introducing evidence-based principles ...
Dec 23, 2015
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St. Louis College of Pharmacy and Washington University School of Medicine in St. Louis are joining forces to find better, safer and more effective ways to use prescription medications to improve health. Researchers from ...
Sep 11, 2015
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Recent research has revealed that many children and adults with autism experience gastrointestinal symptoms and that such symptoms can impact the absorption and availability of medications.
Sep 2, 2014
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