Proposed cancer therapeutic drugs based on blocking the catalytic activities of matrix metalloproteinases (MMPs), which profoundly remodel the environment surrounding a breast cell, have performed poorly in clinical trials. ...
Feb 12, 2013
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(Medical Xpress)—An international team of scientists has observed that the well-studied protein Sirtuin-1, known for helping cells live longer, also appears to play an important role in pancreatic cancer.
Feb 5, 2013
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Researchers have identified a previously unknown critical role for a recently identified immune cell population in the progression of atopic dermatitis. The team found an accumulation of innate lymphoid cells in the active ...
Jan 30, 2013
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(Medical Xpress)—Researchers at the School of Biosciences have identified an unexpected role for a tumour-associated gene in breast cancer.
Jan 18, 2013
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Peanuts are one of the most common triggers of severe food-induced allergic reactions, which can be fatal, and the prevalence of peanut allergy is increasing. However, there is currently no clinical treatment available for ...
Jan 7, 2013
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Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Dec 17, 2012
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A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone ...
Nov 28, 2012
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Six organizations representing physicians, other health care professionals, and patients today issued two new clinical practice guidelines for diagnosing and treating stable ischemic heart disease (IHD), which affects an ...
Nov 19, 2012
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Last year a clinical trial of L-DOPA—a mainstay of Parkinson's disease therapy—was launched for Angelman syndrome, a rare intellectual disorder that shares similar motor symptoms such as tremors and difficulty with balance. ...
Nov 12, 2012
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Researchers in France are taking advantage of the progress in genetic and molecular profiling to analyse the make-up of individual cancer patients' tumours and, using this information, assign them to particular treatments ...
Nov 8, 2012
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