Insights that pave the way for novel therapeutic approaches to tackle cancer, fibrosis, and many age-related conditions have been uncovered by a team of scientists, including researchers from UCL.
20 hours ago
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Multiple myeloma (MM) is one of the most formidable and deadly cancers known to man, with only 50% of patients surviving for more than five years after diagnosis.
Nov 28, 2023
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Psychedelic research has surged in recent years, sparking enthusiasm among clinicians, investors and the general public. Clinical trials are indicating transformative outcomes for people struggling with mental illnesses like ...
Nov 28, 2023
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The first published evidence from humans that semaglutide specifically reduces the symptoms of alcohol use disorder (AUD) has been published in The Journal of Clinical Psychiatry and details a recent collaboration between ...
Nov 28, 2023
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Researchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment strategies were able to help clinical teams determine epilepsy and developmental trajectories for patients ...
Nov 28, 2023
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Health care organizations are looking to artificial intelligence (AI) tools to improve patient care, but their translation into clinical settings has been inconsistent, in part because evaluating AI in health care remains ...
Nov 27, 2023
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Regular dental checkups and oral hygiene visits are important for identifying the early stage of mouth cancer. However, the shortage of dentists in the UK has led to a rise in mouth cancers that are spotted too late, according ...
Nov 27, 2023
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Results from the world's first double-blind, randomized clinical trial to find a treatment for the fungal form of a chronic disabling disease called mycetoma have demonstrated that a new oral treatment, fosravuconazole, is ...
Nov 27, 2023
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Phase III trial results on a precision radiotherapy technique support a "new gold standard" for treating head and neck cancer patients. The research suggests the new approach can reduce the risk of swallowing problems after ...
Nov 24, 2023
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Change in clinical practice would have clear benefits for patients undergoing major bowel surgery, according to analysis conducted by researchers from UCL and the Royal Devon and Exeter Hospital.
Nov 23, 2023
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In clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.
Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.
Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be the pharmaceutical or biotechnology company that developed the agent under study. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization
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