Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor (BDNF) was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators ...
Aug 3, 2018
0
44
Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and ...
Jul 17, 2018
0
2
Cocaine can have a devastating effect on people. It directly stimulates the brain's reward center, and, more importantly, induces long-term changes to the reward circuitry that are responsible for addictive behaviors. Alban ...
Jul 12, 2018
0
0
Unlike with alcohol or nicotine, there is not a pharmacological option available to individuals addicted to cocaine to help them stop using the drug. However, researchers at the University of Alabama at Birmingham believe ...
Jun 28, 2018
1
88
A study in Biological Psychiatry has identified unique genetic changes in the brain's reward circuitry that are associated with cocaine use, including first-time use, withdrawal, and re-exposure to the drug after prolonged ...
May 31, 2018
0
5
Neuroscientists at the University of Sussex have shown by using brain scans of drug users that heroin stimulates a more pleasurable response when taken at home but cocaine is more pleasurable outside the home, such as in ...
May 14, 2018
0
48
Mount Sinai researchers have identified a protein produced by the immune system—granulocyte-colony stimulating factor (G-CSF)—that could be responsible for the development of cocaine addiction.
Jan 16, 2018
0
478
For years, scientists have known that mitochondria in brain cells play a role in brain disorders such as depression, bipolar disorder, anxiety and stress responses. But recently, scientists at the University of Maryland School ...
Dec 20, 2017
0
4
Drug addiction may not require a habitual relationship with a substance, suggests findings from a new model of cocaine administration in rats that better captures the human experience of obtaining and using drugs. The research, ...
Nov 20, 2017
0
1
(Medical Xpress)—A team of researchers working at Columbia University has found a possible link between prior use of alcohol and an increased risk of cocaine addiction. In their paper published on the open access site Science ...
