Neuroscience

Dodging the cognitive hit of early-life seizures

About half of newborns who have seizures go on to have long-term intellectual and memory deficits and cognitive disorders such as autism, but why this occurs has been unknown. In the December 14 Journal of Neuroscience, researchers ...

Alzheimer's disease & dementia

Modulating brain's stress circuity might prevent Alzheimer's disease

In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long-term treatment using a small molecule drug that reduces activity of ...

Medical research

Targeting key gene could help lead to Down syndrome treatment

Targeting a key gene before birth could someday help lead to a treatment for Down syndrome by reversing abnormal embryonic brain development and improving cognitive function after birth, according to a Rutgers-led study.

Medical research

Chemical reaction keeps stroke-damaged brain from repairing itself

Nitric oxide, a gaseous molecule produced in the brain, can damage neurons. When the brain produces too much nitric oxide, it contributes to the severity and progression of stroke and neurodegenerative diseases such as Alzheimer's. ...

Neuroscience

Cognitive decline after surgery tied to brain's own immune cells

After undergoing surgery, elderly patients often experience cloudy thinking that can last for weeks or even months. At one time researchers thought this cognitive decline might be caused by anesthesia, but mounting evidence ...

Alzheimer's disease & dementia

Protein linked to Alzheimer's may also play a role in schizophrenia

A specific protein implicated in the cognitive decline of Alzheimer's disease also appears to play a role in genetic predisposition to schizophrenia, meaning that a drug that targets that protein could treat a variety of ...

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