Oncology & Cancer

Link between colon cancer and metabolism identified

More than 60 years ago Otto Warburg recognized that cancer cells differ from normal cells in the metabolic pathway they use for the oxidation of sugar. Rather than the typical series of oxidative steps that take place in ...

Oncology & Cancer

Researchers discover a key regulator of colon cancer

A team headed by Angel R. Nebreda at the Institute for Research in Biomedicine (IRB) identifies a dual role of the p38 protein in colon cancer. The study demonstrates that, on the one hand, p38 is important for the optimal ...

Oncology & Cancer

Radiation therapy and cancer vaccines: Timing is everything

Radiation therapy fights cancer in more ways than one. Not only does it force cancer cells to self-destruct, but several studies demonstrate that it also activates the immune system to attack tumor cells. This activation ...

Oncology & Cancer

Inflammation mobilizes tumor cells

Ludwig Maximilian University of Munich researchers have discovered a novel feedback mechanism that provides a mechanistic link between chronic inflammation and carcinogenesis.

Oncology & Cancer

Beta-catenin alters T cells in lasting and harmful ways

Activation of beta-catenin, the primary mediator of the ubiquitous Wnt signaling pathway, alters the immune system in lasting and harmful ways, a team of Chicago-based researchers demonstrate in the February 26, 2014, issue ...

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